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Also known as
  • Bensodiazepinderivat sv
  • BZD hr
  • เบนโซไดอะซีปีนส์ th
  • เบนโซไดอะซีปิน th
  • เบ็นโซไดอะซีปีน th
  • เบ็นโซไดอาซีปีน th
  • เบ็นโซไดอาเซพีนส์ th
  • เบนโซไดอะซีพีน th
  • เบนโซไดอะซีพีนส์ th
  • 苯二氮平類藥物 zh-CN
  • Benzodiazepines are a class of psychoactive drugs whose core chemical structure is the fusion of a benzene ring and a diazepine ring. The first such drug, chlordiazepoxide, was discovered accidentally by Leo Sternbach in 1955, and made available in 1960 by Hoffmann–La Roche - which, since 1963, has also marketed the benzodiazepine diazepam. Benzodiazepines enhance the effect of the neurotransmitter gamma-aminobutyric acid at the GABAA receptor, resulting in sedative, hypnotic, anxiolytic, anticonvulsant, and muscle relaxant properties. High doses of many shorter-acting benzodiazepines may also cause anterograde amnesia and dissociation. These properties make benzodiazepines useful in treating anxiety, insomnia, agitation, seizures, muscle spasms, alcohol withdrawal and as a premedication for medical or dental procedures. Benzodiazepines are categorized as either short-, intermediate-, or long-acting. Short- and intermediate-acting benzodiazepines are preferred for the treatment of insomnia; longer-acting benzodiazepines are recommended for the treatment of anxiety.

Freebase Commons Medicine /medicine

Freebase Commons Chemistry /chemistry