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Also known as
  • Bensodiazepinderivat sv
  • Benzodiazepine ro
  • BZD hr
  • เบนโซไดอะซีปีนส์ th
  • เบนโซไดอะซีปิน th
  • เบ็นโซไดอะซีปีน th
  • เบ็นโซไดอาซีปีน th
  • เบ็นโซไดอาเซพีนส์ th
  • เบนโซไดอะซีพีน th
  • เบนโซไดอะซีพีนส์ th
  • Benzodiazepines are a class of psychoactive drugs whose core chemical structure is the fusion of a benzene ring and a diazepine ring. The first such drug, chlordiazepoxide, was discovered accidentally by Leo Sternbach in 1955, and made available in 1960 by Hoffmann–La Roche, which has also marketed the benzodiazepine diazepam since 1963. Benzodiazepines enhance the effect of the neurotransmitter gamma-aminobutyric acid at the GABAA receptor, resulting in sedative, hypnotic, anxiolytic, anticonvulsant, and muscle relaxant properties. High doses of many shorter-acting benzodiazepines may also cause anterograde amnesia and dissociation. These properties make benzodiazepines useful in treating anxiety, insomnia, agitation, seizures, muscle spasms, alcohol withdrawal and as a premedication for medical or dental procedures. Benzodiazepines are categorized as either short-, intermediate-, or long-acting. Short- and intermediate-acting benzodiazepines are preferred for the treatment of insomnia; longer-acting benzodiazepines are recommended for the treatment of anxiety.

Freebase Commons Medicine /medicine

Freebase Commons Chemistry /chemistry