close

  
Filter options:

Freebase Commons Metaweb System Types /type

Object is not asserted on this topic.
Key

Freebase Commons Common /common

Description
  • A tricyclic compound chemically related to tricyclic antidepressants (TCA) with anticonvulsant and analgesic properties. Carbamazepine exerts its anticonvulsant activity by reducing polysynaptic responses and blocking post-tetanic potentiation. Its analgesic activity is not understood; however, carbamazepine is commonly used to treat pain associated with trigeminal neuralgia.
  • Carbamazepine is an anticonvulsant and mood-stabilizing drug used primarily in the treatment of epilepsy and bipolar disorder, as well as trigeminal neuralgia. Off-label uses include attention-deficit hyperactivity disorder, schizophrenia, phantom limb syndrome, complex regional pain syndrome, borderline personality disorder, and post-traumatic stress disorder. Studies on the use of carbamazepine in pregnant women have demonstrated exposure of the fetus to the drug and its metabolites. Intrauterine exposure to carbamazepine has been shown to be teratogenic and is associated with the development of spina bifida, neurodevelopmental problems, craniofacial defects, cardiovascular malformations, hypospadias, and developmental delays. It is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system.

Freebase Commons Medicine /medicine

Freebase Commons Chemistry /chemistry

Chemical Element is not asserted on this topic. Assert type now.

Comments

Hide