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Created by benvvalk on 9/17/2008

Cefalexin ^en

mid: /m/04mdzq notable type: /medicine/drug notable for: /medicine/drug on the web: wikipedia.org

Cefalexin or more commonly cephalexin is a first-generation cephalosporin antibiotic introduced in 1967 by Eli Lilly and Company. It is an orally administered agent with a similar antimicrobial spectrum to the intravenous agents cefalotin and cefazolin. It was first marketed as Keflex, and is marketed under several other trade names. As of 2008, cefalexin was the most popular cephalosporin antibiotic in the United States, with more than 25 million prescriptions of its generic versions alone, for US$255 million in sales. Wikipedia [ - ]

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Cefalexin

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Key /type/object/key

Timestamp /type/object/timestamp

Wednesday, September 17, 2008 12:07 AM

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benvvalk

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benvvalk

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/m/04mdzq

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Cephalexin

Description /common/topic/description

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A beta-lactam, first-generation cephalosporin antibiotic with bactericidal activity. Cephalexin binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linking of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis. Compared to second and third generation cephalosporins, cephalexin is more active against gram-positive and less active against gram-negative organisms.
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Cefalexin or more commonly cephalexin is a first-generation cephalosporin antibiotic introduced in 1967 by Eli Lilly and Company. It is an orally administered agent with a similar antimicrobial spectrum to the intravenous agents cefalotin and cefazolin. It was first marketed as Keflex, and is marketed under several other trade names. As of 2008, cefalexin was the most popular cephalosporin antibiotic in the United States, with more than 25 million prescriptions of its generic versions alone, for US$255 million in sales. Wikipedia

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Topic equivalent webpage /common/topic/topic_equivalent_webpage

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Properties /common/topic/properties

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Article /common/topic/article

Weblink /common/topic/weblink

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Notable for /common/topic/notable_for

Drug

Notable types /common/topic/notable_types

Pronunciation (deprecated) /medicine/drug/pronunciation

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J01DB01

Drugbank /medicine/drug/drugbank

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APRD00250

Pubchem (deprecated) /medicine/drug/pubchem

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CAS Number (deprecated) /medicine/drug/cas_number

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Pharmacological class /medicine/drug/drug_class

Cephalosporin

Brands (deprecated) /medicine/drug/brands

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Route of administration (deprecated) /medicine/drug/route_of_administration

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Pregnancy category /medicine/drug/pregnancy_category

Pregnancy Category B (FDA)

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Prescription drug

ATC Code (deprecated) /medicine/drug/atc_code

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Physiologic effect /medicine/drug/physiologic_effect

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Mechanism of action /medicine/drug/mechanism_of_action

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Marketed formulations /medicine/drug/marketed_formulations

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Active moieties /medicine/drug/active_moieties

Cefalexin

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Part of compound drug (deprecated) /medicine/drug/part_of_compound_drug

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Canonical brands /medicine/drug/canonical_brands

Keflex

Conditions This May Prevent /medicine/condition_prevention_factors/conditions_this_may_prevent

Bacterial Endocarditis United States National Library of Medicine

Side effects /medicine/medical_treatment/side_effects

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Contraindications /medicine/medical_treatment/contraindications

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Trials /medicine/medical_treatment/trials

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Used To Treat /medicine/medical_treatment/used_to_treat

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Active ingredient of formulation /medicine/drug_ingredient/active_ingredient_of_formulation

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Active moiety of formulation /medicine/drug_ingredient/active_moiety_of_formulation

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Active moiety of drug /medicine/drug_ingredient/active_moiety_of_drug

Cefalexin

More general ingredient /medicine/drug_ingredient/more_general_ingredient

Cefalexin

More specific ingredient /medicine/drug_ingredient/more_specific_ingredient

Cefalexin

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Friday, May 24, 2013 9:28 AM

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Formula /chemistry/chemical_compound/formula

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Structure (SMILES) /chemistry/chemical_compound/structure_smiles

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Structure (InChI) /chemistry/chemical_compound/structure_inchi

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InChI Key /chemistry/chemical_compound/inchikey

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CAS ID (deprecated) /chemistry/chemical_compound/cas_id

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IUPAC ID /chemistry/chemical_compound/iuapc_id

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2666

Phase, At STP /chemistry/chemical_compound/phase_at_stp

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Average Molar Mass /chemistry/chemical_compound/average_molar_mass

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Critical point temperature /chemistry/chemical_compound/critical_point_temperature

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Triple point temperature /chemistry/chemical_compound/triple_point_temperature

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Triple point pressure /chemistry/chemical_compound/triple_point_pressure

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Enthalpy Change of Fusion /chemistry/chemical_compound/enthalpy_change_of_fusion

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Entropy Change of Fusion /chemistry/chemical_compound/entropy_change_of_fusion

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Enthalpy Change of Vaporization /chemistry/chemical_compound/enthalpy_change_of_vaporization

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Entropy Change of Vaporization /chemistry/chemical_compound/entropy_change_of_vaporization

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Enthalpy Change of Formation, Solid /chemistry/chemical_compound/enthalpy_change_of_formation_solid

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Molar Entropy, Solid /chemistry/chemical_compound/molar_entropy_solid

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Heat Capacity, Solid /chemistry/chemical_compound/heat_capacity_solid

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Enthalpy Change of Formation, Liquid /chemistry/chemical_compound/enthalpy_change_of_formation_liquid

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Molar Entropy, Liquid /chemistry/chemical_compound/molar_entropy_liquid

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Heat Capacity, Liquid /chemistry/chemical_compound/heat_capacity_liquid

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Enthalpy Change of Formation, Gas /chemistry/chemical_compound/enthalpy_change_of_formation_gas

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Molar Entropy, Gas /chemistry/chemical_compound/molar_entropy_gas

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Heat Capacity, Gas /chemistry/chemical_compound/heat_capacity_gas

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Classifications /chemistry/chemical_compound/classifications

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Density /chemistry/chemical_compound/density

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Vapor pressure /chemistry/chemical_compound/vapor_pressure

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Solubility /chemistry/chemical_compound/solubility

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CAS ID /chemistry/chemical_element/cas_id

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15686-71-2

Symbol /chemistry/chemical_element/symbol

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Electronegativity (Pauling scale) /chemistry/chemical_element/electronegativity

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Covalent radius /chemistry/chemical_element/covalent_radius

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Van der Waals radius /chemistry/chemical_element/van_der_waals_radius

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Melting Point /chemistry/chemical_element/melting_point

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Boiling Point /chemistry/chemical_element/boiling_point

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Periodic table block /chemistry/chemical_element/periodic_table_block

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Ionization Energy /chemistry/chemical_element/ionization_energy

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URI /user/benvvalk/default_domain/moby_output_descriptor/uri

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http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#Cephalexin

Pronunciation /base/schemastaging/context_name/pronunciation

IPA	Yomigana	Pinyin	Zhuyin	Text	Value of property
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Official name /base/schemastaging/context_name/official_name

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Culinary /base/schemastaging/context_name/culinary

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Medical /base/schemastaging/context_name/medical

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Chemistry /base/schemastaging/context_name/chemistry

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Biology /base/schemastaging/context_name/biology

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Regional variants /base/schemastaging/context_name/regional_variants

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Common name /base/schemastaging/context_name/common_name

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Keflex

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