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Freebase Commons Metaweb System Types /type

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Freebase Commons Common /common

  • A cancer arising from the epithelial cells that line the lumen of the colon.
  • Colorectal cancer is the development of cancer in the colon or rectum. It is due to the abnormal growth of cells that have the ability to invade or spread to other parts of the body. Signs and symptoms may include blood in the stool, a change in bowel movements, weight loss, and feeling tired all the time. Most colorectal cancers are due to lifestyle factors and increasing age, with only a small number of cases due to inherited genetic disorders. Risk factors include diet, obesity, smoking, and not enough physical activity. Dietary factors that increase the risk include red and processed meat, as well as alcohol. Another risk factor is inflammatory bowel disease, which includes Crohn's disease and ulcerative colitis. Some of the inherited conditions that can cause colorectal cancer include: familial adenomatous polyposis and hereditary non-polyposis colon cancer; however, these represent less than 5% of cases. It typically starts as a benign tumor which over time becomes cancerous. Bowel cancer may be diagnosed by obtaining a sample of the colon during a sigmoidoscopy or colonoscopy. This is then followed by medical imaging to determine if the disease has spread.

Freebase Commons Medicine /medicine