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  • Earl Wilbur Sutherland, Jr. was an American pharmacologist and biochemist born in Burlingame, Kansas. Sutherland won a Nobel Prize in Physiology or Medicine in 1971 "for his discoveries concerning the mechanisms of the action of hormones," especially epinephrine, via second messengers, namely cyclic adenosine monophosphate, or cyclic AMP. Sutherland died on March 9, 1974 in Miami, Florida, at the age of 58.

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Year Award category Award winner Winning work Ceremony Achievement level Notes/Description
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  • "for his discoveries concerning the mechanisms of the action of hormones"
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  • For his discovery of cyclic AMP, and for providing a comprehension of this key chemical mechanism, which regulates hormonal action.
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  • For the discovery that epinephrine and hormones of the pituitary gland occasion their diverse regulatory effects by initiating cellular synthesis of cyclic adenylic acid, now recognized as a universal biological second messenger, which opened a new level of understanding of the subtle mechanisms that integrate the chemical life of the cell while offering hope of entirely new approaches to chemotherapy.
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  • "In recognition of his outstanding contributions to our understanding of the central role the adenylcyclase system plays in mediating many of the effects of hormones on metabolic processes.These discoveries, which emanated from a careful, imaginative and thorough analysis of the mechanisms by which epinephrine and glucagon increased glycogenolysis, have opened new fields for exploration."

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