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Created by benvvalk on 9/17/2008

Etacrynic acid ^en

mid: /m/07fjfr notable type: /medicine/drug notable for: /medicine/drug on the web: wikipedia.org

Etacrynic acid or ethacrynic acid, trade name Edecrin, is a loop diuretic used to treat high blood pressure and the swelling caused by diseases like congestive heart failure, liver failure, and kidney failure. Unlike the other loop diuretics, etacrynic acid is not a sulfonamide and thus, its use is not contraindicated in those with sulfa allergies. Etacrynic acid is a phenoxyacetic acid derivative containing a ketone group and a methylene group. A cysteine adduct is formed with the methylene group and this is the active form. Wikipedia [ - ]

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Etacrynic acid

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Wednesday, September 17, 2008 12:23 AM

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benvvalk

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benvvalk

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An aryloxy-acetic acid derivative belonging to the class of loop diuretics. Ethacrynic acid interferes with the chloride binding site of the Na+, K+, Cl- cotransporter system in the thick ascending loop of Henle, thereby inhibiting the reabsorption of sodium, potassium, and chloride ions. This leads to an increase in the excretion of sodium, potassium, chloride, calcium, and water.
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Etacrynic acid or ethacrynic acid, trade name Edecrin, is a loop diuretic used to treat high blood pressure and the swelling caused by diseases like congestive heart failure, liver failure, and kidney failure. Unlike the other loop diuretics, etacrynic acid is not a sulfonamide and thus, its use is not contraindicated in those with sulfa allergies. Etacrynic acid is a phenoxyacetic acid derivative containing a ketone group and a methylene group. A cysteine adduct is formed with the methylene group and this is the active form. Wikipedia

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Drug

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ATC Code /medicine/drug/atccode

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Drugbank /medicine/drug/drugbank

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Pubchem (deprecated) /medicine/drug/pubchem

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CAS Number (deprecated) /medicine/drug/cas_number

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Pharmacological class /medicine/drug/drug_class

Diuretic
Loop diuretic

Brands (deprecated) /medicine/drug/brands

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Route of administration (deprecated) /medicine/drug/route_of_administration

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Pregnancy category /medicine/drug/pregnancy_category

Pregnancy Category B (FDA)

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Prescription drug

ATC Code (deprecated) /medicine/drug/atc_code

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Physiologic effect /medicine/drug/physiologic_effect

Increased Diuresis at Loop of Henle

Mechanism of action /medicine/drug/mechanism_of_action

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Active moieties /medicine/drug/active_moieties

Etacrynic acid

Active moiety of (deprecated) /medicine/drug/active_moiety_of

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Part of compound drug (deprecated) /medicine/drug/part_of_compound_drug

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Canonical brands /medicine/drug/canonical_brands

Edecrin

Side effects /medicine/medical_treatment/side_effects

Contraindications /medicine/medical_treatment/contraindications

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Trials /medicine/medical_treatment/trials

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Used To Treat /medicine/medical_treatment/used_to_treat

Active ingredient of formulation /medicine/drug_ingredient/active_ingredient_of_formulation

Ethacrynic acid 25 tablet

Active moiety of formulation /medicine/drug_ingredient/active_moiety_of_formulation

Active moiety of drug /medicine/drug_ingredient/active_moiety_of_drug

More general ingredient /medicine/drug_ingredient/more_general_ingredient

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Ethacrynate Sodium

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Friday, May 17, 2013 9:14 AM

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Formula /chemistry/chemical_compound/formula

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Structure (SMILES) /chemistry/chemical_compound/structure_smiles

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Structure (InChI) /chemistry/chemical_compound/structure_inchi

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InChI Key /chemistry/chemical_compound/inchikey

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CAS ID (deprecated) /chemistry/chemical_compound/cas_id

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IUPAC ID /chemistry/chemical_compound/iuapc_id

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Phase, At STP /chemistry/chemical_compound/phase_at_stp

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Average Molar Mass /chemistry/chemical_compound/average_molar_mass

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Critical point temperature /chemistry/chemical_compound/critical_point_temperature

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Critical point pressure /chemistry/chemical_compound/critical_point_pressure

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Triple point temperature /chemistry/chemical_compound/triple_point_temperature

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Triple point pressure /chemistry/chemical_compound/triple_point_pressure

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Enthalpy Change of Fusion /chemistry/chemical_compound/enthalpy_change_of_fusion

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Entropy Change of Fusion /chemistry/chemical_compound/entropy_change_of_fusion

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Enthalpy Change of Vaporization /chemistry/chemical_compound/enthalpy_change_of_vaporization

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Entropy Change of Vaporization /chemistry/chemical_compound/entropy_change_of_vaporization

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Enthalpy Change of Formation, Solid /chemistry/chemical_compound/enthalpy_change_of_formation_solid

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Molar Entropy, Solid /chemistry/chemical_compound/molar_entropy_solid

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Heat Capacity, Solid /chemistry/chemical_compound/heat_capacity_solid

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Enthalpy Change of Formation, Liquid /chemistry/chemical_compound/enthalpy_change_of_formation_liquid

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Molar Entropy, Liquid /chemistry/chemical_compound/molar_entropy_liquid

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Heat Capacity, Liquid /chemistry/chemical_compound/heat_capacity_liquid

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Enthalpy Change of Formation, Gas /chemistry/chemical_compound/enthalpy_change_of_formation_gas

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Molar Entropy, Gas /chemistry/chemical_compound/molar_entropy_gas

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Heat Capacity, Gas /chemistry/chemical_compound/heat_capacity_gas

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Classifications /chemistry/chemical_compound/classifications

Phenoxyacetates

Density /chemistry/chemical_compound/density

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Solubility /chemistry/chemical_compound/solubility

Solvent	Solubility
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URI /user/benvvalk/default_domain/moby_output_descriptor/uri

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http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#Ethacrynic_Acid

Pronunciation /base/schemastaging/context_name/pronunciation

IPA	Yomigana	Pinyin	Zhuyin	Text	Value of property
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Culinary /base/schemastaging/context_name/culinary

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Medical /base/schemastaging/context_name/medical

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Edecrin

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