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  • The medial lemniscus, also known as Reil's band or Reil's ribbon, is a large ascending bundle of heavily myelinated axons that decussate in the brain stem, specifically in the medulla. The medial lemniscus is formed by the crossings of internal arcuate fibers. The internal arcuate fibers are composed of axons of nucleus gracilis and nucleus cuneatus. The axons of the nucleus gracilis and nucleus cuneatus in the medial lemniscus have cell bodies that lie in the contralaterally. Lesion of the medial lemnisci causes an impairment of vibratory and touch-pressure sense. The medial lemniscus is part of the medial lemniscus pathway, which ascends from the skin to the thalamus.

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