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Freebase Commons Metaweb System Types /type

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Freebase Commons Common /common

  • A primary or metastatic malignant tumor involving the pancreas. Representative examples include carcinoma and lymphoma.
  • Pancreatic cancer occurs when cancer cells develop from the pancreas, a glandular organ located behind the stomach. Signs and symptoms of pancreatic cancer may include abdominal or back pain, yellow skin, unexplained weight loss, light colored stools, dark urine and loss of appetite. Early on there are usually no symptoms. Symptoms that are specific enough to suspect pancreatic cancer often do not appear until the disease is already in an advanced stage. By the time of diagnosis the cancer has usually spread to other parts of the body. Risk factors include: smoking, obesity, diabetes, and certain rare genetic conditions including: multiple endocrine neoplasia type 1 and hereditary nonpolyposis colon cancer among others. Smoking is the cause of about 20% of cases while 10% of cases are linked to inherited genes. Infiltrating ductal adenocarcinoma is the most common type of pancreatic cancer, making up 90% of cases, and references to pancreatic cancer often refer only to that type. It arises within the part of the pancreas that makes digestive enzymes, known as the exocrine pancreas. One to two percent arise from islet cells, and are classified as neuroendocrine tumors.

Freebase Commons Medicine /medicine