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Freebase Commons Common /common

  • A primary or metastatic malignant tumor involving the pancreas. Representative examples include carcinoma and lymphoma.
  • Pancreatic cancer occurs when cancer cells develop from the pancreas, a glandular organ located behind the stomach. There are a number of different types of pancreatic cancer, but pancreatic adenocarcinoma represents about 85% of all cases. Signs and symptoms of pancreatic cancer may include abdominal or back pain, yellow skin, unexplained weight loss, light colored stools, dark urine and loss of appetite. Early on there are usually no symptoms. Symptoms that are specific enough to suspect pancreatic cancer often do not appear until the disease is already in an advanced stage. By the time of diagnosis the cancer has usually spread to other parts of the body. Pancreatic cancer is rare in those younger than 40, and the median age of diagnosis is 71. Risk factors include: smoking, obesity, diabetes, and certain rare genetic conditions including: multiple endocrine neoplasia type 1 and hereditary nonpolyposis colon cancer among others. About 25% of cases are attributable to tobacco smoking, while 5-10% of cases are linked to inherited genes.

Freebase Commons Medicine /medicine