close

Freebase is currently in read-only mode

Topic

Created by benvvalk on 9/17/2008

Streptozotocin ^en

mid: /m/09v9_v notable type: /medicine/drug notable for: /medicine/drug on the web: wikipedia.org

Streptozotocin is a naturally occurring chemical that is particularly toxic to the insulin-producing beta cells of the pancreas in mammals. It is used in medicine for treating certain cancers of the Islets of Langerhans and used in medical research to produce an animal model for Type 1 diabetes in large dose as well as Type 2 diabetes with multiple low doses. Wikipedia [ - ]

Add type

Metaweb System Types

Object

Common

Topic

Medicine

Drug
Medical Treatment
Drug ingredient

Freebase

Object profile

benvvalk's types

NCI Term

Schema staging

Context name
Drug extra

Object is not asserted on this topic.

ID /type/object/id

-

GUID /type/object/guid

#9202a8c04000641f80000000009d27fa

Type /type/object/type

Topic
Drug
NCI Term
Drug ingredient
Drug extra
Medical Treatment United States National Library of Medicine
Context name

Name /type/object/name

- - Edit
  - Delete
Streptozotocin

8 values total »

Key /type/object/key

Timestamp /type/object/timestamp

Wednesday, September 17, 2008 1:04 AM

Permission /type/object/permission

/boot/all_permission

Creator /type/object/creator

benvvalk

Attribution /type/object/attribution

benvvalk

Search /type/object/search

-

Machine ID /type/object/mid

/m/09v9_v

Also known as /common/topic/alias

- - Edit
  - Delete
Streptozocin

Description /common/topic/description

- - Edit
  - Delete
A methylnitrosourea antineoplastic antibiotic isolated from the bacterium Streptomyces achromogenes. Streptozocin alkylates DNA, forming inter-strand DNA cross-links and inhibiting DNA synthesis. Due to its glucose moiety, this agent is readily taken up by pancreatic beta cells, inducing diabetes mellitus at high concentrations. Unlike other nitrosoureas, streptozocin causes little myelosuppression. (NCI04)
- - Edit
  - Delete
Streptozotocin is a naturally occurring chemical that is particularly toxic to the insulin-producing beta cells of the pancreas in mammals. It is used in medicine for treating certain cancers of the Islets of Langerhans and used in medical research to produce an animal model for Type 1 diabetes in large dose as well as Type 2 diabetes with multiple low doses. Wikipedia

9 values total »

Image /common/topic/image

Official website /common/topic/official_website

-

Topic equivalent webpage /common/topic/topic_equivalent_webpage

17 values total »

Social media presence /common/topic/social_media_presence

-

Topical webpage /common/topic/topical_webpage

-

Subjects /common/topic/subjects

-

Subject of /common/topic/subject_of

-

Web Link(s) (deprecated) /common/topic/webpage

-

Properties /common/topic/properties

-

Article /common/topic/article

Weblink /common/topic/weblink

-

Notable for /common/topic/notable_for

Drug

Notable types /common/topic/notable_types

Pronunciation (deprecated) /medicine/drug/pronunciation

-

ATC Code /medicine/drug/atccode

-

Drugbank /medicine/drug/drugbank

-

Pubchem (deprecated) /medicine/drug/pubchem

-

CAS Number (deprecated) /medicine/drug/cas_number

-

Pharmacological class /medicine/drug/drug_class

Alkylating agent

Brands (deprecated) /medicine/drug/brands

-

Route of administration (deprecated) /medicine/drug/route_of_administration

-

Pregnancy category /medicine/drug/pregnancy_category

Pregnancy Category D (FDA)

Legal status /medicine/drug/legal_status

Prescription drug

ATC Code (deprecated) /medicine/drug/atc_code

-

Physiologic effect /medicine/drug/physiologic_effect

-

Mechanism of action /medicine/drug/mechanism_of_action

Alkylating Activity

Marketed formulations /medicine/drug/marketed_formulations

Streptozocin 100 powder for solution

Active moieties /medicine/drug/active_moieties

Streptozotocin

Active moiety of (deprecated) /medicine/drug/active_moiety_of

-

Part of compound drug (deprecated) /medicine/drug/part_of_compound_drug

-

Canonical brands /medicine/drug/canonical_brands

Zanosar

Side effects /medicine/medical_treatment/side_effects

-

Contraindications /medicine/medical_treatment/contraindications

-

Trials /medicine/medical_treatment/trials

-

Used To Treat /medicine/medical_treatment/used_to_treat

Active ingredient of formulation /medicine/drug_ingredient/active_ingredient_of_formulation

Streptozocin 100 powder for solution

Active moiety of formulation /medicine/drug_ingredient/active_moiety_of_formulation

Streptozocin 100 powder for solution

Active moiety of drug /medicine/drug_ingredient/active_moiety_of_drug

Streptozotocin

More general ingredient /medicine/drug_ingredient/more_general_ingredient

-

More specific ingredient /medicine/drug_ingredient/more_specific_ingredient

-

Object profile is not asserted on this topic. Assert type now.

Object generation time /freebase/object_profile/object_generation_time

- - Edit
  - Delete
Friday, May 17, 2013 9:14 AM

Link count /freebase/object_profile/link_count

-

URI /user/benvvalk/default_domain/moby_output_descriptor/uri

- - Edit
  - Delete
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#Streptozocin

Pronunciation /base/schemastaging/context_name/pronunciation

IPA	Yomigana	Pinyin	Zhuyin	Text	Value of property
-

Nickname /base/schemastaging/context_name/nickname

-

Official name /base/schemastaging/context_name/official_name

-

Former name /base/schemastaging/context_name/former_name

-

Abbreviation /base/schemastaging/context_name/abbreviation

-

Culinary /base/schemastaging/context_name/culinary

-

Medical /base/schemastaging/context_name/medical

-

Chemistry /base/schemastaging/context_name/chemistry

-

Biology /base/schemastaging/context_name/biology

-

Short name /base/schemastaging/context_name/short_name

-

Original name /base/schemastaging/context_name/original_name

-

Sports /base/schemastaging/context_name/sports

-

Disputed name preferred form /base/schemastaging/context_name/disputed_name_preferred_form

-

Regional variants /base/schemastaging/context_name/regional_variants

Variant name	Preferred in regions
-

Common name /base/schemastaging/context_name/common_name

- - Edit
  - Delete
Zanosar

Pseudonym /base/schemastaging/context_name/pseudonym

-

Plural /base/schemastaging/context_name/plural

-

Comments

Hide