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Freebase Commons Common /common

  • Spironolactone and hydrochlorothiazide (Mylan Pharmaceuticals), manufactured drug form of Spironolactone and hydrochlorothiazide, 25mg/tablet hydrochlorothiazide ; 25mg/tablet spironolactone tablet, NDC 0378-0141

Freebase Commons Business /business

Freebase Commons Medicine /medicine

Section name Section URI Prominent warning Highlight text Subject manufactured drug Section LOINC code
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  • Spironolactone has been shown to be a tumorigen in chronic toxicity studies in rats (see PRECAUTIONS). Spironolactone and hydrochlorothiazide should be used only in those conditions described under INDICATIONS AND USAGE. Unnecessary use of this drug should be avoided. Fixed-dose combination drugs are not indicated for initial therapy of edema or hypertension. Edema or hypertension requires therapy titrated to the individual patient. If the fixed combination represents the dosage so determined, its use may be more convenient in patient management. The treatment of hypertension and edema is not static but must be reevaluated as conditions in each patient warrant.
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  • 34068-7

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