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  • Stanford researchers have developed an assay for subtyping diffuse large B-cell lymphoma (DLBCL) patients based upon the gene expression profiles in DLBCL sample tissue. The method involves the correlation of gene expression in tumor samples from DLBCL patients for the classification of disease characteristics such as patient survival. From this analysis, the expression level of a set of six genes can be used as a predictive model of patient survival. Since current methods for risk stratification of DLBCL patients such as the IPI do not take into account genetic factors, this method fills a significant clinical need.

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