Drug formulation en
A drug formulation is a preparation of one or more drug moieties that has a specific pharmaceutical makeup and profile. It is characterized by a set of active chemical compounds (specific versions, not moieties), the strengths of those active compounds, the dosage form in which they are available, and the route(s) by which that dosage form is administered. Two drugs should only be considered the same formulation if they are pharmaceutically equivalent. Note that it is possible that a single drug formulation may be available in multiple manufactured forms that differ in bioequivalence, resulting in a different clinical effect and/or safety profile. See the Therapeutic equivalents property on the Manufactured drug form as the way to represent bioequivalence. Drug formulations should be named using the nonproprietary name of the drug formulation, typically consisting of the active chemical compounds concatenated with and, e.g. Ethinyl estradiol and norgestimate. Brand/trade names, excluding the nonproprietary name, should be captured in the Brand names property, and can be added to the Aliases property as well for better findability. [ - ]
What are Properties? Properties
| Property | ID | Expected Type | Description | |
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| Active ingredients | /medicine/drug_formulation/active_ingredients | /medicine/drug_ingredient |
The active substance or substances in this drug formulation. For many drug formulations, the active ingredients will be the specific forms (salts, esters, other noncovalent derivatives, etc) of the active moieties used in this preparation. Note that some active ingredients may not be drugs proper, but other chemical compounds, botanicals, etc that are considered active by the drug maker or regulator (such as sodium chloride). , |
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| Strength | /medicine/drug_formulation/strength | /medicine/drug_strength |
The strength of the constituent chemical compounds in this drug formulation. For drug formulations that have multiple active chemical compounds, multiple strengths should be specified, one for each active chemical compound. , |
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| Dosage form | /medicine/drug_formulation/dosage_form | /medicine/drug_dosage_form |
The physical form in which this drug is made available, for example tablet, injection, capsule, etc. , , |
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| Routes of administration | /medicine/drug_formulation/routes | /medicine/drug_administration_route |
The route(s) of administration, or path(s) by which this drug is brought into contact with the body. , |
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| Brand names | /medicine/drug_formulation/brand_names | /type/text |
Brand names in which this formulation is available. |
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| Drug category | /medicine/drug_formulation/drug_category | /medicine/drug_formulation_category |
What kind of drug this is, for example, chemical, cellular therapy, plasma derivative, vaccine, etc. |
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| Formulation of | /medicine/drug_formulation/formulation_of | /medicine/drug |
The drug that this is a formulation of. |
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| Active ingredient moieties | /medicine/drug_formulation/active_ingredient_moieties | /medicine/drug_ingredient |
The active ingredients in this drug formulation, expressed as moieties. A moiety is the part of a drug that makes the drug work the way it does, i.e. the molecule or ion, excluding those appended portions of the molecule that cause the drug to be an ester, salt (including a salt with hydrogen or coordination bonds), or other noncovalent derivative (such as a complex, chelate, or clathrate) of the molecule, responsible for the physiological or pharmacological action of the drug substance. |
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| Active moieties | /medicine/drug_formulation/active_moieties | /medicine/drug |
DEPRECATED - use /medicine/drug_formulation/active_ingredient_moieties. The active ingredients in this drug formulation, expressed as moieties. A moiety is the part of a drug that makes the drug work the way it does, i.e. the molecule or ion, excluding those appended portions of the molecule that cause the drug to be an ester, salt (including a salt with hydrogen or coordination bonds), or other noncovalent derivative (such as a complex, chelate, or clathrate) of the molecule, responsible for the physiological or pharmacological action of the drug substance. , , |
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| Pregnancy category | /medicine/drug_formulation/pregnancy_category | /medicine/drug_pregnancy_category |
The pregnancy category of a drug formulation is an assessment of the risk of fetal injury due to the drug formulation, when used by the mother during pregnancy. |
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| Legal status | /medicine/drug_formulation/legal_status | /medicine/drug_legal_status |
The legal status of this drug formulation, as defined by government bodies that regulate therapeutic goods. |
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| Manufactured forms | /medicine/drug_formulation/manufactured_forms | /medicine/manufactured_drug_form |
Pharmaceutically-equivalent forms in which this formulation is manufactured or made available. Important: all manufactured forms must be pharmaceutically equivalent (same active compounds, strengths, dosage form, routes), but need not be therapeutically equivalent. |
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| Reference form | /medicine/drug_formulation/reference_form | /medicine/manufactured_drug_form |
If there is a reference manufactured form of this drug defined by a regulating entity, this property points to it. For example, in the US, certain drugs are designated by the FDA as reference drugs, and are used as standards for defining therapeutic equivalence. |
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What are Included Types? Included Types
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This type doesn't have any included types. |
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Incoming Properties
| Originating Type | Property | ||
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Manufactured drug form
/medicine/manufactured_drug_form
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Manufactured form of
/medicine/manufactured_drug_form/manufactured_form_of
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Drug formulation category
/medicine/drug_formulation_category
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Drug formulations in this category
/medicine/drug_formulation_category/drug_formulations
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Drug
/medicine/drug
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Marketed formulations
/medicine/drug/marketed_formulations
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Drug dosage form
/medicine/drug_dosage_form
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Formulations available in this form
/medicine/drug_dosage_form/formulations_available_in_this_form
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Drug strength
/medicine/drug_strength
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Drug formulations available in this strength
/medicine/drug_strength/drug_formulations
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Drug
/medicine/drug
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Active moiety of
/medicine/drug/active_moiety_of
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Drug ingredient
/medicine/drug_ingredient
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Active ingredient of formulation
/medicine/drug_ingredient/active_ingredient_of_formulation
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Drug administration route
/medicine/drug_administration_route
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Drug formulations
/medicine/drug_administration_route/drug_formulations
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Drug ingredient
/medicine/drug_ingredient
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Active moiety of formulation
/medicine/drug_ingredient/active_moiety_of_formulation
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Drug pregnancy category
/medicine/drug_pregnancy_category
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Drug formulation
/medicine/drug_pregnancy_category/drug_formulation
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