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760 BV: Product topics matching:
Filter this Collection| x name | x image | x Technology involved | x Sales | x article | |
|---|---|---|---|---|---|
| x Amount | x Currency | ||||
| x Panitumumab | Monoclonal Antibody | 170,000,000 |
Panitumumab (INN), formerly ABX-EGF, is a fully human monoclonal antibody specific to the epidermal growth factor receptor (also known as EGF receptor, EGFR, ErbB-1 and HER1 in humans).
Panitumumab is manufactured by Amgen and marketed as Vectibix....
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| Humanized Monoclonal Antibody | 39,000,000 | ||||
| x Cinacalcet |
|
321,000,000 |
Cinacalcet (INN) is a drug that acts as a calcimimetic (i.e. it mimics the action of calcium on tissues) by allosteric activation of the calcium-sensing receptor that is expressed in various human organ tissues. It is sold by Amgen under the trade...
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| 463,000,000 | |||||
| 157,000,000 | |||||
| x Darbepoetin alfa | 3,600,000,000 |
Darbepoetin alfa (rINN) (pronounced /dɑrbəˈpɔɪtɨn/) is a synthetic form of erythropoietin. It stimulates erythropoiesis (increases red blood cell levels) and is used to treat anemia, commonly associated with chronic renal failure and cancer...
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| 4,121,000,000 | |||||
| 3,273,000,000 | |||||
| x Etanercept |
|
Therapeutics | 2,879,000,000 |
Etanercept (Enbrel) is a drug that treats autoimmune diseases by interfering with the TNF receptor (a part of the immune system) by acting as a TNF inhibitor.
Etanercept is a fusion protein produced through expression of recombinant DNA. That is, it...
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| 3,230,000,000 | |||||
| 2,573,000,000 | |||||
| x Palifermin |
Palifermin (Kepivance, Biovitrum) is a human recombinant keratinocyte growth factor (KGF) produced in Escherichia coli.
Palifermin costs approximately 5,000 Euros per treatment for a 70 kg patient
When patients with blood cancers undergo high dose...
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| x Anakinra |
|
Anakinra (Kineret) is a drug used to treat rheumatoid arthritis.
Anakinra is an interleukin-1 (IL-1) receptor antagonist. Anakinra blocks the biologic activity of naturally occurring IL-1, including inflammation and cartilage degradation associated...
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| x Pegfilgrastim | Nanomedicine | 3,923,000,000 |
Pegfilgrastim is a immunostimulator which functions as a PEGylated granulocyte colony-stimulating factor. Amgen manufactures pegfilgrastim under the brand name Neulasta.
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| 4,277,000,000 | |||||
| 3,504,000,000 | |||||
| x Filgrastim |
|
Filgrastim is a granulocyte colony-stimulating factor (G-CSF) analog used to stimulate the proliferation and differentiation of granulocytes. It is produced by recombinant DNA technology. The gene for human granulocyte colony-stimulating factor is...
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| x TNKase | |||||
| x ACTIVASE | 268,000,000 | ||||
| 218,000,000 | |||||
| 243,000,000 | |||||
| x Nutropin | 370,000,000 | ||||
| 371,000,000 | |||||
| 378,000,000 | |||||
| x Dornase alfa | 186,000,000 | ||||
| 223,000,000 | |||||
| 199,000,000 | |||||
| x Oncotype DX |
|
Personalized medicine | 64,000,000 |
Oncotype DX, created by Genomic Health, is a diagnostic test that quantifies the likelihood of disease recurrence in women with early-stage breast cancer and assesses the likely benefit from certain types of chemotherapy.
Oncotype DX was developed...
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| Real-time polymerase chain reaction | 29,200,000 | ||||
| x Irinotecan | Personalized medicine | 969,000,000 |
Irinotecan (Camptosar, Pfizer; Campto, Yakult Honsha) is a drug used for the treatment of cancer.
Irinotecan is a topoisomerase 1 inhibitor, which prevents DNA from unwinding. Chemically, it is a semisynthetic analogue of the natural alkaloid...
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| 903,000,000 | |||||
| 910,000,000 | |||||
| x AmpliChip CYP450 Test |
|
Personalized medicine |
AmpliChip CYP450 Test is a clinical test from Roche. The test aims to find the specific gene types (a genotype) of the patient that will determine how he or she metabolizes certain medicines, therefore guides the doctors to prescribe medicine for...
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| Diagnostics | |||||
| Biomarker | |||||
| Genomics | |||||
| Molecular Diagnostics | |||||
| more ▼ | |||||
| x TruGene-HIV 1 Genotyping Kit | Personalized medicine | ||||
| x Imatinib |
|
Personalized medicine |
Imatinib is a drug used to treat certain types of cancer. It is currently marketed by Novartis as Gleevec (USA) or Glivec (Europe/Australia) as its mesylate salt, imatinib mesilate (INN). It was originally coded during development as CGP57148B or...
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| Therapeutics | |||||
| x Familion 5-gene profile | Personalized medicine | ||||
| x Tamoxifen |
|
Personalized medicine |
Tamoxifen is an antagonist of the estrogen receptor in breast tissue. It has been the standard endocrine (anti-estrogen) therapy for hormone-positive early breast cancer, although aromatase inhibitors have been proposed for postmenopausal women....
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| x AlloMap | Personalized medicine | ||||
| x BRCA 1-2 Test | Personalized medicine | ||||
| x Mercaptopurine |
|
Personalized medicine |
Mercaptopurine (also called 6-mercaptopurine, 6-MP or its brand name Purinethol) is an immunosuppressive drug.
It is a thiopurine.
It is used to treat leukemia. It is also used for pediatric non-Hodgkin's lymphoma, polycythemia vera, psoriatic...
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| x Zeno Acne Treatment | |||||
| x Abelcet | Nanomedicine | ||||
| x Amphotec | Nanomedicine | ||||
| x Ambisome | Nanomedicine | 262,571,000 | US$ | ||
| 223,031,000 | US$ | ||||
| x DaunoXome | Nanomedicine | ||||
| x Doxil/Caefyx | Nanomedicine | ||||
| x Depocyt | Nanomedicine | ||||
| x Epaxal Berna | Nanomedicine | ||||
| Vaccine | |||||
| x Inflexal V Berna | Nanomedicine | ||||
| x Myocet | Nanomedicine | ||||
| x Visudyne | Nanomedicine | ||||
| x Estrasorb | Nanomedicine | ||||
| x Adagen | Nanomedicine | ||||
| x Oncaspar | Nanomedicine | ||||
| x PEGASYS | Nanomedicine |
Pegylated interferon alfa-2a (40 kDa; commercial name Pegasys) is an antiviral drug discovered at the pharmaceutical company F. Hoffmann-La Roche; it has a dual mode of action - both antiviral and on the immune system. The additon of polyethylene...
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| x PEG-Intron | Nanomedicine | ||||
| x Macugen | Nanomedicine | ||||
| x Somavert | Nanomedicine | ||||
| x Copaxone | Nanomedicine | ||||
| x Renagel | Nanomedicine | 417,500,000 | US$ | ||
| 515,100,000 | US$ | ||||
| 602,700,000 | US$ | ||||
| x Emend | Nanomedicine |
(aprepitant) is an antiemetic that can be used in conjunction with other antiemetic medications to prevent nausea and vomiting in patients undergoing chemotherapy in a condition known as chemotherapy-induced nausea and vomiting or CINV. The drug is...
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| x Megace ESc | Nanomedicine | ||||
| x Rapamune | Nanomedicine | ||||
| x Tricorc | Nanomedicine | ||||
| x Triglidec | Nanomedicine | ||||
| x Abraxane | Nanomedicine | 324,692 | US$ | ||
| Nanoparticle Drug Delivery | 174,906 | US$ | |||
| 133,731 | US$ | ||||
| x Rituximab | Monoclonal Antibody | 2,300,000,000 |
Rituximab, sold under the trade names Rituxan and MabThera, is a chimeric monoclonal antibody against the protein CD20, which is primarily found on the surface of B cells. Rituximab is used in the treatment of many lymphomas, leukemias, and some...
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| Chimeric Monoclonal Antibody | 1,831,000,000 | ||||
| 2,071,000,000 | |||||
| x Trastuzumab |
|
Monoclonal Antibody | 747,000,000 |
Trastuzumab (Herceptin) is a monoclonal antibody that interferes with the HER2/neu receptor.
The HER receptors are proteins that are embedded in the cell membrane and communicate molecular signals from outside the cell to inside the cell, and turn...
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| Humanized Monoclonal Antibody | 1,300,000,000 | ||||
| 1,234,000,000 | |||||
| x Palivizumab | Monoclonal Antibody | 1,063,000,000 |
Palivizumab (brand name Synagis or Abbosynagis) is a monoclonal antibody produced by recombinant DNA technology. It is used in the prevention of Respiratory Syncytial Virus (RSV) infections. It is recommended for certain infants that are high-risk ...
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| Humanized Monoclonal Antibody | 1,065,000,000 | ||||
| 860,000,000 | |||||
| x Adalimumab |
|
Monoclonal Antibody | 2,000,000,000 |
Adalimumab (HUMIRA, Abbott) is the third TNF inhibitor, after infliximab and etanercept, to be approved in the United States. Like infliximab and etanercept, adalimumab binds to TNFα, preventing it from activating TNF receptors; adalimumab was...
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| Human Monoclonal Antibody | 3,000,000,000 | ||||
| Antibody Phage Display Technology | 1,400,000,000 | ||||
| x Bevacizumab | Monoclonal Antibody | 1,133,000,000 |
Bevacizumab (trade name Avastin, Genentech/Roche) is a humanized monoclonal antibody that recognises and blocks vascular endothelial growth factor (VEGF). VEGF is a chemical signal that stimulates the growth of new blood vessels (angiogenesis)....
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| Humanized Monoclonal Antibody | 1,746,000,000 | ||||
| 2,300,000,000 | |||||
| x Abciximab | Monoclonal Antibody |
Abciximab (previously known as c7E3 Fab), manufactured by Centocor and distributed by Eli Lilly under the trade name ReoPro, is a platelet aggregation inhibitor mainly used during and after coronary artery procedures like angioplasty to prevent...
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| Chimeric Monoclonal Antibody | |||||
| x Omalizumab |
|
Monoclonal Antibody | 425,000,000 |
Omalizumab (Xolair, Genentech / Novartis) is a humanized antibody drug approved for patients with moderate-to-severe or severe allergic asthma, which is caused by hypersensitivity reactions to certain harmless environmental substances. Omalizumab's...
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| Humanized Monoclonal Antibody | 470,000,000 | ||||
| 321,000,000 | |||||
| x Alemtuzumab |
|
Monoclonal Antibody |
Alemtuzumab (marketed as Campath, MabCampath or Campath-1H) is a monoclonal antibody used in the treatment of chronic lymphocytic leukemia (CLL), cutaneous T cell lymphoma (CTCL) and T-cell lymphoma.
Alemtuzumab targets CD52, a protein present on...
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| Humanized Monoclonal Antibody | |||||
| x Muromonab | Monoclonal Antibody |
Muromonab-CD3 (generic name) is a monoclonal antibody (mAb), also known as Orthoclone OKT3 (Brand name). It is a mouse-derived (murine) monoclonal antibody that specifically binds to the CD3 (T3) protein found on the surface of T cells.
Of...
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| Murine Monoclonal Antibody | |||||
| x Efalizumab | Monoclonal Antibody | 107,000,000 |
Efalizumab (trade name Raptiva, Genentech, Merck Serono) is a medication designed to treat psoriasis. As its name implies, it is a recombinant humanized monoclonal antibody that binds to CD11a and acts as an immunosuppressant. It is administered...
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| Humanized Monoclonal Antibody | 90,000,000 | ||||
| 79,000,000 | |||||
| x Basiliximab |
|
Monoclonal Antibody |
Basiliximab (trade name Simulect) is a chimeric mouse-human monoclonal antibody to the α chain (CD25) of the IL-2 receptor of T cells. It is used to prevent rejection in organ transplantation, especially in kidney transplants. It is a Novartis...
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| Humanized Monoclonal Antibody | |||||
| x Gemtuzumab ozogamicin | Monoclonal Antibody |
Gemtuzumab ozogamicin (marketed by Wyeth as Mylotarg) is a monoclonal antibody used to treat acute myelogenous leukemia.
It is a monoclonal antibody to CD33 linked to a cytotoxic agent from the class of calicheamicins. CD33 is expressed in most...
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| Humanized Monoclonal Antibody | |||||
