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x Panitumumab   Monoclonal Antibody 170,000,000 Drug
Panitumumab (INN), formerly ABX-EGF, is a fully human monoclonal antibody specific to the epidermal growth factor receptor (also known as EGF receptor, EGFR, ErbB-1 and HER1 in humans). Panitumumab is manufactured by Amgen and marketed as Vectibix....
Humanized Monoclonal Antibody 39,000,000 Medical Treatment
BV: Therapeutic
x Cinacalcet Cinacalcet Structural Formulae   321,000,000 Drug
Cinacalcet (INN) is a drug that acts as a calcimimetic (i.e. it mimics the action of calcium on tissues) by allosteric activation of the calcium-sensing receptor that is expressed in various human organ tissues. It is sold by Amgen under the trade...
463,000,000 BV: Therapeutic
157,000,000 Medical Treatment
x Darbepoetin alfa     3,600,000,000 Drug
Darbepoetin alfa (rINN) (pronounced /dɑrbəˈpɔɪtɨn/) is a synthetic form of erythropoietin. It stimulates erythropoiesis (increases red blood cell levels) and is used to treat anemia, commonly associated with chronic renal failure and cancer...
4,121,000,000 BV: Therapeutic
3,273,000,000 Medical Treatment
x Etanercept Enbrel Therapeutics 2,879,000,000 Drug
Etanercept (Enbrel) is a drug that treats autoimmune diseases by interfering with the TNF receptor (a part of the immune system) by acting as a TNF inhibitor. Etanercept is a fusion protein produced through expression of recombinant DNA. That is, it...
3,230,000,000 BV: Therapeutic
2,573,000,000 Medical Treatment
x Palifermin       Drug
Palifermin (Kepivance, Biovitrum) is a human recombinant keratinocyte growth factor (KGF) produced in Escherichia coli. Palifermin costs approximately 5,000 Euros per treatment for a 70 kg patient When patients with blood cancers undergo high dose...
Medical Treatment
BV: Therapeutic
x Anakinra Anakinra     Drug
Anakinra (Kineret) is a drug used to treat rheumatoid arthritis. Anakinra is an interleukin-1 (IL-1) receptor antagonist. Anakinra blocks the biologic activity of naturally occurring IL-1, including inflammation and cartilage degradation associated...
Medical Treatment
BV: Therapeutic
x Pegfilgrastim   Nanomedicine 3,923,000,000 Drug
Pegfilgrastim is a immunostimulator which functions as a PEGylated granulocyte colony-stimulating factor. Amgen manufactures pegfilgrastim under the brand name Neulasta.
4,277,000,000 Medical Treatment
3,504,000,000 BV: Therapeutic
x Filgrastim Filgrastim     Drug
Filgrastim is a granulocyte colony-stimulating factor (G-CSF) analog used to stimulate the proliferation and differentiation of granulocytes. It is produced by recombinant DNA technology. The gene for human granulocyte colony-stimulating factor is...
BV: Therapeutic
x TNKase       BV: Therapeutic  
x ACTIVASE     268,000,000 BV: Therapeutic  
218,000,000
243,000,000
x Nutropin     370,000,000 BV: Therapeutic  
371,000,000
378,000,000
x Dornase alfa     186,000,000 BV: Therapeutic  
223,000,000
199,000,000
x Oncotype DX Oncotype DX Personalized medicine 64,000,000  
Oncotype DX, created by Genomic Health, is a diagnostic test that quantifies the likelihood of disease recurrence in women with early-stage breast cancer and assesses the likely benefit from certain types of chemotherapy. Oncotype DX was developed...
Real-time polymerase chain reaction 29,200,000
x Irinotecan   Personalized medicine 969,000,000 Drug
Irinotecan (Camptosar, Pfizer; Campto, Yakult Honsha) is a drug used for the treatment of cancer. Irinotecan is a topoisomerase 1 inhibitor, which prevents DNA from unwinding. Chemically, it is a semisynthetic analogue of the natural alkaloid...
903,000,000 Medical Treatment
910,000,000 BV: Therapeutic Molecule
BV: Therapeutic
x AmpliChip CYP450 Test amplichip Personalized medicine    
AmpliChip CYP450 Test is a clinical test from Roche. The test aims to find the specific gene types (a genotype) of the patient that will determine how he or she metabolizes certain medicines, therefore guides the doctors to prescribe medicine for...
Diagnostics
Biomarker
Genomics
Molecular Diagnostics
more
x TruGene-HIV 1 Genotyping Kit   Personalized medicine      
x Imatinib Imatinib chemical structure Personalized medicine   Drug
Imatinib is a drug used to treat certain types of cancer. It is currently marketed by Novartis as Gleevec (USA) or Glivec (Europe/Australia) as its mesylate salt, imatinib mesilate (INN). It was originally coded during development as CGP57148B or...
Therapeutics Medical Treatment
x Familion 5-gene profile   Personalized medicine      
x Tamoxifen Tamoxifen Personalized medicine   Drug
Tamoxifen is an antagonist of the estrogen receptor in breast tissue. It has been the standard endocrine (anti-estrogen) therapy for hormone-positive early breast cancer, although aromatase inhibitors have been proposed for postmenopausal women....
Medical Treatment
Risk Factor
x AlloMap   Personalized medicine      
x BRCA 1-2 Test   Personalized medicine      
x Mercaptopurine Mercaptopurine Personalized medicine   Drug
Mercaptopurine (also called 6-mercaptopurine, 6-MP or its brand name Purinethol) is an immunosuppressive drug. It is a thiopurine. It is used to treat leukemia. It is also used for pediatric non-Hodgkin's lymphoma, polycythemia vera, psoriatic...
Medical Treatment
x Zeno Acne Treatment          
x Abelcet   Nanomedicine   BV: Therapeutic  
x Amphotec   Nanomedicine   BV: Therapeutic  
x Ambisome   Nanomedicine 262,571,000 BV: Therapeutic  
223,031,000 Drug
Medical Treatment
x DaunoXome   Nanomedicine   BV: Therapeutic  
x Doxil/Caefyx   Nanomedicine   BV: Therapeutic  
Drug
Medical Treatment
x Depocyt   Nanomedicine   BV: Therapeutic  
x Epaxal Berna   Nanomedicine   BV: Therapeutic  
Vaccine
x Inflexal V Berna   Nanomedicine   BV: Therapeutic  
x Myocet   Nanomedicine   BV: Therapeutic  
x Visudyne   Nanomedicine   BV: Therapeutic  
x Estrasorb   Nanomedicine   BV: Therapeutic  
x Adagen   Nanomedicine   BV: Therapeutic  
x Oncaspar   Nanomedicine   BV: Therapeutic  
x PEGASYS   Nanomedicine   Drug
Pegylated interferon alfa-2a (40 kDa; commercial name Pegasys) is an antiviral drug discovered at the pharmaceutical company F. Hoffmann-La Roche; it has a dual mode of action - both antiviral and on the immune system. The additon of polyethylene...
Medical Treatment
BV: Therapeutic
x PEG-Intron   Nanomedicine   BV: Therapeutic  
x Macugen   Nanomedicine   BV: Therapeutic  
Drug
Medical Treatment
x Somavert   Nanomedicine   BV: Therapeutic  
x Copaxone   Nanomedicine   BV: Therapeutic  
x Renagel   Nanomedicine 417,500,000 BV: Therapeutic  
515,100,000 Drug
602,700,000 Medical Treatment
x Emend   Nanomedicine   BV: Therapeutic
(aprepitant) is an antiemetic that can be used in conjunction with other antiemetic medications to prevent nausea and vomiting in patients undergoing chemotherapy in a condition known as chemotherapy-induced nausea and vomiting or CINV. The drug is...
Drug
Medical Treatment
x Megace ESc   Nanomedicine   BV: Therapeutic  
x Rapamune   Nanomedicine   BV: Therapeutic  
x Tricorc   Nanomedicine   BV: Therapeutic  
x Triglidec   Nanomedicine   BV: Therapeutic  
x Abraxane   Nanomedicine 324,692 BV: Therapeutic  
Nanoparticle Drug Delivery 174,906
133,731
x Rituximab   Monoclonal Antibody 2,300,000,000 Drug
Rituximab, sold under the trade names Rituxan and MabThera, is a chimeric monoclonal antibody against the protein CD20, which is primarily found on the surface of B cells. Rituximab is used in the treatment of many lymphomas, leukemias, and some...
Chimeric Monoclonal Antibody 1,831,000,000 Medical Treatment
2,071,000,000 BV: Therapeutic
x Trastuzumab Trastuzumab chemical structure Monoclonal Antibody 747,000,000 Drug
Trastuzumab (Herceptin) is a monoclonal antibody that interferes with the HER2/neu receptor. The HER receptors are proteins that are embedded in the cell membrane and communicate molecular signals from outside the cell to inside the cell, and turn...
Humanized Monoclonal Antibody 1,300,000,000 Medical Treatment
1,234,000,000 BV: Therapeutic
x Palivizumab   Monoclonal Antibody 1,063,000,000 Drug
Palivizumab (brand name Synagis or Abbosynagis) is a monoclonal antibody produced by recombinant DNA technology. It is used in the prevention of Respiratory Syncytial Virus (RSV) infections. It is recommended for certain infants that are high-risk ...
Humanized Monoclonal Antibody 1,065,000,000 Medical Treatment
860,000,000 BV: Therapeutic
x Adalimumab Adalimumab structure Monoclonal Antibody 2,000,000,000 Drug
Adalimumab (HUMIRA, Abbott) is the third TNF inhibitor, after infliximab and etanercept, to be approved in the United States. Like infliximab and etanercept, adalimumab binds to TNFα, preventing it from activating TNF receptors; adalimumab was...
Human Monoclonal Antibody 3,000,000,000 BV: Therapeutic
Antibody Phage Display Technology 1,400,000,000 Medical Treatment
x Bevacizumab   Monoclonal Antibody 1,133,000,000 Drug
Bevacizumab (trade name Avastin, Genentech/Roche) is a humanized monoclonal antibody that recognises and blocks vascular endothelial growth factor (VEGF). VEGF is a chemical signal that stimulates the growth of new blood vessels (angiogenesis)....
Humanized Monoclonal Antibody 1,746,000,000 Medical Treatment
2,300,000,000 BV: Therapeutic
x Abciximab   Monoclonal Antibody   Drug
Abciximab (previously known as c7E3 Fab), manufactured by Centocor and distributed by Eli Lilly under the trade name ReoPro, is a platelet aggregation inhibitor mainly used during and after coronary artery procedures like angioplasty to prevent...
Chimeric Monoclonal Antibody Medical Treatment
BV: Therapeutic
x Omalizumab Xolair Monoclonal Antibody 425,000,000 Drug
Omalizumab (Xolair, Genentech / Novartis) is a humanized antibody drug approved for patients with moderate-to-severe or severe allergic asthma, which is caused by hypersensitivity reactions to certain harmless environmental substances. Omalizumab's...
Humanized Monoclonal Antibody 470,000,000 BV: Therapeutic
321,000,000 Medical Treatment
x Alemtuzumab Alemtuzumab Fab 1CE1 Monoclonal Antibody   Drug
Alemtuzumab (marketed as Campath, MabCampath or Campath-1H) is a monoclonal antibody used in the treatment of chronic lymphocytic leukemia (CLL), cutaneous T cell lymphoma (CTCL) and T-cell lymphoma. Alemtuzumab targets CD52, a protein present on...
Humanized Monoclonal Antibody Medical Treatment
BV: Therapeutic
x Muromonab   Monoclonal Antibody   Drug
Muromonab-CD3 (generic name) is a monoclonal antibody (mAb), also known as Orthoclone OKT3 (Brand name). It is a mouse-derived (murine) monoclonal antibody that specifically binds to the CD3 (T3) protein found on the surface of T cells. Of...
Murine Monoclonal Antibody BV: Therapeutic
Medical Treatment
x Efalizumab   Monoclonal Antibody 107,000,000 Drug
Efalizumab (trade name Raptiva, Genentech, Merck Serono) is a medication designed to treat psoriasis. As its name implies, it is a recombinant humanized monoclonal antibody that binds to CD11a and acts as an immunosuppressant. It is administered...
Humanized Monoclonal Antibody 90,000,000 Medical Treatment
79,000,000 BV: Therapeutic
x Basiliximab Basiliximab Monoclonal Antibody   Drug
Basiliximab (trade name Simulect) is a chimeric mouse-human monoclonal antibody to the α chain (CD25) of the IL-2 receptor of T cells. It is used to prevent rejection in organ transplantation, especially in kidney transplants. It is a Novartis...
Humanized Monoclonal Antibody Medical Treatment
BV: Therapeutic
x Gemtuzumab ozogamicin   Monoclonal Antibody   Drug
Gemtuzumab ozogamicin (marketed by Wyeth as Mylotarg) is a monoclonal antibody used to treat acute myelogenous leukemia. It is a monoclonal antibody to CD33 linked to a cytotoxic agent from the class of calicheamicins. CD33 is expressed in most...
Humanized Monoclonal Antibody Medical Treatment
BV: Therapeutic
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