Anatumomab mafenatox is a mouse monoclonal antibody which is used to treat non-small cell lung cancer.
It is a fusion protein with an enterotoxin ('mafenatox') of Staphylococcus aureus.
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Abagovomab is a mouse anti-idiotype monoclonal antibody whose variable epitope mirrors a tumour antigen (CA-125) highly expressed in the epithelial ovarian cancer. Abagovomab does not bind directly to CA-125, but it works as a "surrogate" antigen, enabling the immune system to identify and attack... -
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Capromab
Indium (In) capromab pendetide (trade name Prostascint) is a mouse monoclonal antibody used to image the extent of prostate cancer. The antibody itself, capromab, is linked to pendetide, a derivative of DTPA. Pendetide acts as a chelating agent for the radionuclide indium-111. The detection is done... -
Altumomab
Indium (In) altumomab pentetate (trade name Hybri-ceaker) is a mouse monoclonal antibody linked to pentetate which acts as a chelating agent for the radioisotope indium-111. The drug is used for the diagnosis of colorectal cancer. -
Fanolesomab
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Tositumomab is a drug for the treatment of follicular lymphoma. It is a IgG2a anti-CD20 monoclonal antibody derived from immortalized mouse cells. Tositumomab is applied in a sequential infusion followed by iodine (I) tositumomab, which is the same antibody covalently bound to the radionuclide...
