Cardiovascular disease: Trials Filter Medical trial topics

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Cardiovascular disease

Cardiovascular disease

Cardiovascular disease or cardiovascular diseases is the class of diseases that involve the heart or blood vessels (arteries and veins). While the term technically refers to any disease that affects the cardiovascular system (as used in MeSH), it is usually used to refer to those related to...
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Hypertension Prevention Trial (HPT) Feasibility Study

To test the feasibility and the efficacy of nutritional interventions in the primary prevention of hypertension in individuals predisposed to the development of hypertension; specifically, to test the hypothesis that reduction of weight and/or...

Minimum age for eligibility:

  • 25

Maximum age for eligibility:

  • 49

Phase:

Eligibility inclusion criteria:

  • Some mild to moderately obese subjects.
  • ,
  • Diastolic blood pressure between 78 and 89 mm Hg.
  • ,
  • Not on a special diet or antihypertensive medication at entry.
  • ,
  • Free of major disease.

Eligibile genders:

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Type of trial:

ClinicalTrials.gov Identifier:

  • NCT00000501

Start date:

  • Sep 1981

Vitamin E and C to Slow Progression of Common Carotid Artery Plaque Build-up

This study will evaluate the effects of vitamin E supplementation in retarding the progression of common carotid artery intima-media thickening in African Americans.   BACKGROUND: Evidence from epidemiologic studies, and from one unpublished study...

Minimum age for eligibility:

  • 35

Maximum age for eligibility:

  • 59

Primary outcomes:

  • rate of change in average common carotid artery intima-media thickness (measured over 24 months)

Eligibility exclusion criteria:

  • Healthy

Phase:

Eligibility inclusion criteria:

  • African-American

Eligibile genders:

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Type of trial:

ClinicalTrials.gov Identifier:

  • NCT00000600

Treatment being tested:

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Start date:

  • Jun 1995

Postmenopausal Hormone Therapy in Unstable Angina

To determine if estrogen therapy in postmenopausal women with unstable angina reduces the incidence of ischemic episodes.   BACKGROUND: Unstable angina is a frequent diagnosis in post-menopausal women and is associated with a significant risk of...

Minimum age for eligibility:

  • 45

Maximum age for eligibility:

  • 75

End date:

  • Jun 2000

Phase:

Eligibility inclusion criteria:

  • Postmenopausal women with unstable angina.

Eligibile genders:

Type of trial:

ClinicalTrials.gov Identifier:

  • NCT00000601

Start date:

  • Jul 1995

Physicians' Health Study

To assess the effect on cardiovascular mortality of alternate-day consumption of 325 milligrams of aspirin and, secondarily, the effect on cancer incidence of alternate-day consumption of 50 milligrams of beta-carotene. BACKGROUND: Thrombosis plays a...

Minimum age for eligibility:

  • 40

Maximum age for eligibility:

  • 84

Eligibility exclusion criteria:

  • No history of stroke, myocardial infarction, cancer, or renal disease.
  • ,
  • No contraindications to aspirin or beta-carotene
  • ,
  • No current usage of aspirin or Vitamin A tables greater than once per week.

Phase:

Eligibility inclusion criteria:

  • Male physicians

Eligibile genders:

Type of trial:

ClinicalTrials.gov Identifier:

  • NCT00000500

Treatment being tested:

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Start date:

  • Sep 1981
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