Chlamydia trachomatis, an obligate intracellular human pathogen, is one of three bacterial species in the genus Chlamydia. C. trachomatis is Gram-indeterminate (i.e. cannot be stained with the Gram stain); structurally the organism is Gram-negative. Identified in 1907, C. trachomatis was the first chlamydial agent discovered in humans.
C. trachomatis includes three human biovars: trachoma (serovars A, B, Ba or C), urethritis (serovars D-K), and l...
more
Chlamydia trachomatis, an obligate intracellular human pathogen, is one of three bacterial species in the genus Chlamydia. C. trachomatis is Gram-indeterminate (i.e. cannot be stained with the Gram stain); structurally the organism is Gram-negative. Identified in 1907, C. trachomatis was the first chlamydial agent discovered in humans.
C. trachomatis includes three human biovars: trachoma (serovars A, B, Ba or C), urethritis (serovars D-K), and lymphogranuloma venereum (LGV, serovars L1, 2 and 3). Many, but not all, C. trachomatis strains have an extrachromosomal plasmid.
Chlamydia species are readily identified and distinguished from other chlamydial species using DNA-based tests.
Most strains of C. trachomatis are recognized by monoclonal antibodies (mAbs) to epitopes in the VS4 region of MOMP. However, these mAbs may also cross-react with two other Chlamydia species, C. suis and C. muridarum.
C. trachomatis is a obligate intracellular pathogen (i.e. the bacterium lives within human...
less
