Choh Hao Li (sometimes Cho Hao Li) (Chinese: 李卓皓; pinyin: Lǐ Zhuōhào) (April 21 1913—November 28, 1987) was a Chinese-born U.S. biochemist who discovered, in 1966, that human pituitary growth hormone (somatotropin) consists of a chain of 256 amino acids. In 1970 he succeeded in synthesizing this hormone, the largest protein molecule synthesized up to that time.
Li was born in Guangzhou and educated at the Nanjing University. In 1935 he emigrated ...
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Choh Hao Li (sometimes Cho Hao Li) (Chinese: 李卓皓; pinyin: Lǐ Zhuōhào) (April 21 1913—November 28, 1987) was a Chinese-born U.S. biochemist who discovered, in 1966, that human pituitary growth hormone (somatotropin) consists of a chain of 256 amino acids. In 1970 he succeeded in synthesizing this hormone, the largest protein molecule synthesized up to that time.
Li was born in Guangzhou and educated at the Nanjing University. In 1935 he emigrated to the USA, where he took up postgraduate studies at the University of California at Berkeley and later joined the staff. He became professor in 1950. In 1955 he was elected as Academician of Academia Sinica, Republic of China.
Li spent his entire academic career studying the pituitary-gland hormones. In collaboration with various co-workers, he isolated several protein hormones, including adreno-corticotrophic hormone (ACTH), which stimulates the adrenal cortex to increase its secretion of corticoids. In 1956, Li and his group showed that...
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