Donald James Cram (April 22, 1919 – June 17, 2001) was an American chemist who shared the 1987 Nobel Prize in Chemistry with Jean-Marie Lehn and Charles J. Pedersen "for their development and use of molecules with structure-specific interactions of high selectivity." They were the founders of the field of host-guest chemistry.
Cram was born in Chester, Vermont, and died in Palm Desert, California. He was the originator of Cram's rule, which provi...
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Donald James Cram (April 22, 1919 – June 17, 2001) was an American chemist who shared the 1987 Nobel Prize in Chemistry with Jean-Marie Lehn and Charles J. Pedersen "for their development and use of molecules with structure-specific interactions of high selectivity." They were the founders of the field of host-guest chemistry.
Cram was born in Chester, Vermont, and died in Palm Desert, California. He was the originator of Cram's rule, which provides a model for predicting the outcome of nucleophilic attack of carbonyl compounds. He published more than 418 publications that have been cited some 27,000 times (h-index 88) and he wrote seven books.
Cram went to Winwood High School, Long Island, N.Y., and then to Rollins College, Florida, from 1938 to 1941. He received his master's degree from the University of Nebraska–Lincoln in 1942, with Norman O. Cromwell as his thesis adviser. He subject was "Amino ketones, mechanism studies of the reactions of heterocyclic secondary amines with ...
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