Granuloma inguinale (also known as "Donovanosis" and "Granuloma venereum") is a bacterial disease that has reached endemic proportions in many underdeveloped regions. Because of the scarcity of medical treatment, the disease often goes untreated. The disease is characterized by painless genital ulcers which can be mistaken for syphilis. However, they ultimately progress to destruction of internal and external tissue, with leakage of mucus and blo...
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Granuloma inguinale (also known as "Donovanosis" and "Granuloma venereum") is a bacterial disease that has reached endemic proportions in many underdeveloped regions. Because of the scarcity of medical treatment, the disease often goes untreated. The disease is characterized by painless genital ulcers which can be mistaken for syphilis. However, they ultimately progress to destruction of internal and external tissue, with leakage of mucus and blood. The destructive nature of donovanosis also increases the risk of superinfection by other pathogenic microbes.
The first known name for this condition was "serpiginous ulcer", which dates to 1882..
The proper clinical designation for donovanosis is granuloma inguinale. Granuloma is a nodular type of inflammatory reaction, and inguinale refers to the inguinal region, which is commonly involved in this infection. The disease is commonly known as donovanosis, after the Donovan Bodies which are a diagnostic sign.
The causative organism,...
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