Duragesic and Durogesic (pronounced /ˌdɜrəˈdʒiːzɪk/) are trade names of fentanyl transdermal therapeutic systems, and are used for relief of moderate to severe pain. Since Duragesic/Durogesic release Fentanyl, a potent opioid, slowly through the skin, one patch may provide 72 hours of pain relief. Its initial onset after a patch has been applied is roughly 8–12 hours under normal conditions, thus Duragesic patches are often prescribed with anothe...
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Duragesic and Durogesic (pronounced /ˌdɜrəˈdʒiːzɪk/) are trade names of fentanyl transdermal therapeutic systems, and are used for relief of moderate to severe pain. Since Duragesic/Durogesic release Fentanyl, a potent opioid, slowly through the skin, one patch may provide 72 hours of pain relief. Its initial onset after a patch has been applied is roughly 8–12 hours under normal conditions, thus Duragesic patches are often prescribed with another opioid (such as morphine sulfate) to handle breakthrough pain.
Duragesic was first approved by the CBG in the Netherlands on 17 July 1995 as 25, 50, 75 and 100 µg/hr formulations after a set of successful clinical trials, and on October 27 2004 the 12 µg/hr formulation was approved as well. On Jan 28, 2005, the U.S. Food and Drug Administration approved first-time generic formulations of 25, 50, 75, and 100 µg/hr fentanyl transdermal systems (made by Mylan Technologies, Inc.; brand name Duragesic, made by Alza Corp.) through an FTC consent...
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