Graft-versus-host disease

Graft-versus-host disease (GVHD) is a common complication of allogeneic bone marrow transplantation in which functional immune cells in the transplanted marrow recognize the recipient as "foreign" and mount an immunologic attack. It can also take place in a blood transfusion under certain circumstances. According to the 1959 Billingham Criteria, 3 criteria must be met in order for GVHD to occur. After bone marrow transplantation, T cells present ... more
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