Humanized Monoclonal Antibody
Facts from the Community
From the BioVenturist base
Products involving this technology:
- Trastuzumab
- Palivizumab
- Omalizumab
- Efalizumab
- Alemtuzumab
- Bevacizumab
- Daclizumab
- Gemtuzumab ozogamicin
- SGN-40
- Lintuzumab
Parent Technology:
Similar topics in Freebase
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Monoclonal Antibody
Monoclonal antibodies (mAb or moAb) are monospecific antibodies that are identical because they are produced by one type of immune cell that are all clones of a single parent cell. Given almost any substance, it is possible to create monoclonal antibodies that specifically bind to that substance;... -
Human Monoclonal Antibody
'Human' Monoclonal Antibodies can be created in a variety of ways, including the use of transgenic animals with their immunoglobulin loci replaced with human ones. -
Protein Therapeutics
Protein therapeutics is the broad class of therapeutics that involve administering proteins. This includes replacing a deficient protein in a patient, to targeting a molecule of interest with a protein capture agent (antibody), to protein vaccines. -
Chimeric Monoclonal Antibody
Chimeric mABs are constructed from murine variable regions with the constant domain of human IgG. -
Antibody-Drug Conjugate (ADC)
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Murine Monoclonal Antibody
A murine monoclonal antibody is an antibody derived from mouse.