John W. Holter (April 1, 1916 - December 22, 2003) was a toolmaker working for the Yale and Town Lock Company Stamford Connecticut. His son Charles Case "Casey" Holter was born on November 7, 1955 with a severe form of spina bifida. Shortly after birth he contracted meningitis, which caused his head to expand rapidly. His parents were told that he had developed "water on the brain" or hydrocephalus.
As luck would have it Holter's son was being lo...
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John W. Holter (April 1, 1916 - December 22, 2003) was a toolmaker working for the Yale and Town Lock Company Stamford Connecticut. His son Charles Case "Casey" Holter was born on November 7, 1955 with a severe form of spina bifida. Shortly after birth he contracted meningitis, which caused his head to expand rapidly. His parents were told that he had developed "water on the brain" or hydrocephalus.
As luck would have it Holter's son was being looked after in Philadelphia, where the surgeons Nulsen and Spitz had already demonstrated that a ventricle-to-atrium diversion system could work. What they needed was an inexpensive and practical valve that could control the direction of the flow and maintain normal cranial pressure.
A chance discovery showed Holter, after a failed attempt in which a young boy died, that he could use a silicone one-way valve (pressure sealing). After refinement of the silicone and rubber to a medically suitable grade it was patented and manufactured as Silastic...
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