A Krukenberg tumor, also Krukenberg tumour, classically refers to a metastatic ovarian malignancy whose primary site arose in the gastrointestinal tract or breast. Diffuse gastric carcinoma (linitis plastica) used to be the most common, but lately there have been an increase in breast origin . Krukenberg tumors are often found in both ovaries. Microscopically, they are characterized by appearance of mucin-secreting signet-ring cells in the tissue...
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A Krukenberg tumor, also Krukenberg tumour, classically refers to a metastatic ovarian malignancy whose primary site arose in the gastrointestinal tract or breast. Diffuse gastric carcinoma (linitis plastica) used to be the most common, but lately there have been an increase in breast origin . Krukenberg tumors are often found in both ovaries. Microscopically, they are characterized by appearance of mucin-secreting signet-ring cells in the tissue of the ovary; when the primary tumor is discovered, the same signet-ring cells are typically found.
The Krukenberg tumor is named after Friedrich Ernst Krukenberg (1871-1946), a German doctor who first described them as "fibrosarcoma ovarii mucocellulare carcinomatodes".
Metastatic cancer of the ovary accounts for only about 5% of ovarian cancer; in the remainder, the ovary is the primary cancer site. Krukenberg tumors are the third most common metastatic ovarian cancer (after epithelial and germ-cell tumors) and make up 14% of these cancers...
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