Multi-drug resistant tuberculosis (MDR-TB) is defined as TB that is resistant at least to isoniazid (INH) and rifampicin (RMP), the two most powerful first-line anti-TB drugs. Isolates that are multiply-resistant to any other combination of anti-TB drugs but not to INH and RMP are not classed as MDR-TB.
MDR-TB mostly develop in the course of the treatment of fully sensitive TB and this is the result of patients missing doses, doctors giving inapp...
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Multi-drug-resistant tuberculosis
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