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National Institute on Drug Abuse
The National Institute on Drug Abuse (NIDA) is a United States federal-government research institute whose mission is to "lead the Nation in bringing the power of science to bear on drug abuse and addiction."
NIDA's roots can be traced back to 1935, when a research facility (named the Addiction...
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Medical trial
- ClinicalTrials.gov Identifier
- » Sponsor
- » Type of trial
- » Design
- Primary outcomes
- Secondary outcomes
- Start date
- End date
- Last follow-up
- » Phase
- Expected total enrollment
- » Eligibile genders
- Minimum age for eligibility
- Maximum age for eligibility
- Eligibility inclusion criteria
- Eligibility exclusion criteria
- » Location
- » Health authority
- » Contact
- » References
- » Diseases
- » Treatment being tested
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Pharmacological Modulation of Cocaine Effects – 1
The purpose of this study is to conduct human laboratory studies of possible cocaine interactions with various potential treatment medications.
Expected total enrollment:
- 0
End date:
- Dec 2001
Phase:
Diseases:
Location:
Eligibile genders:
Health authority:
Type of trial:
ClinicalTrials.gov Identifier:
- NCT00000201
Treatment being tested:
Design:
Feasibility Study of Take-Home LAAM Medication – 3
The purpose of this study is to test therapeutic benefits of take-home LAAM. (1) Do subjects with take-home LAAM availability show increased clinical responsibility over subjects without; (2) Do subjects with take-home LAAM attempt diversion when...
Minimum age for eligibility:
- 18
Expected total enrollment:
- 0
Primary outcomes:
- Drug Use ,
- Decreased frequency of HIV related behavior ,
- Increased prosocial behaviors ,
- Retention
Eligibility exclusion criteria:
- Hypertensive to LAAM ,
- Female of childbearing potential who refuses to use an acceptable form of birth control ,
- Pregnant or nursing women ,
- Medical or psychiatric illness which would jeopardize safe study participation
Phase:
Eligibility inclusion criteria:
- Meets DSM-IV criteria for opiate dependence ,
- Willing to provide names, addresses, and numbers of 3 relatives who can aid in patient location for follow-up visits ,
- Able to understand English ,
- Certified for LAAM treatment by a physician
Diseases:
Location:
Health authority:
Type of trial:
ClinicalTrials.gov Identifier:
- NCT00000300
Sponsor:
Treatment being tested:
Design:
Start date:
- Mar 1995
Cocaine Effects in Humans: Physiology and Behavior – 1
The purpose of this study is to compare the effects of buprenorphine or methadone maintenance on cocaine taking and on the physiological and subjective effects of cocaine, including cocaine craving, in opiate-dependent cocaine users.
Minimum age for eligibility:
- 18
Expected total enrollment:
- 19
Maximum age for eligibility:
- 45
Primary outcomes:
- Interaction of cocaine and meds on cardio ,
- Effects of medication on cocaine craving ,
- Interaction of cocaine & meds on coc's subjective
Eligibility exclusion criteria:
- Healthy
Phase:
Diseases:
Health authority:
Type of trial:
ClinicalTrials.gov Identifier:
- NCT00000200
Treatment being tested:
Design:
Start date:
- Jan 1997
Rapid Evaluation of Amantadine for Treatment of Cocaine Abuse/Dependence – 4
The purpose of this study is to empirically test a series of medications to: 1) determine each medication's efficacy in treatment of cocaine abuse/dependence; 2) find most effective dose range for each medication. In this study, amantadine is tested...
Minimum age for eligibility:
- 18
Expected total enrollment:
- 0
Maximum age for eligibility:
- 65
Primary outcomes:
- Cocaine craving ,
- Cocaine use ,
- Psychosocial progress ,
- Retention
Eligibility exclusion criteria:
- Healthy
Phase:
Diseases:
Health authority:
ClinicalTrials.gov Identifier:
- NCT00000301
Sponsor:
Treatment being tested:
Start date:
- Mar 1996
