A humanized monoclonal antibody directed against the epidermal growth factor receptor (EGFR) with potential antineoplastic activity. Nimotuzumab binds to and inhibits EGFR, resulting in growth inhibition of tumor cells that overexpress EGFR. This agent may act synergistically with radiation therapy.
Nimotuzumab
Medicine
CAS Number:
- 828933-51-3
Drug class:
Route of administration:
Trials:
- Nimotuzumab in advanced head and neck tumors in combination with radiotherapy and radiochemotherapy
- Nimotuzumab in recurrent or relapsed children high grade gliomas
- Nimotuzumab in Adults With Anaplastic Astrocytomas and Glioblastoma Multiforme
Used To Treat:
Facts from the Community
From the BioVenturist base
Developed by:
Brand Names:
- Theraloc
- BIOMAb EGFR
- CIMAher
- TheraCIM
Stage of development:
Target/Biomolecule of Interest:
therapeutic molecule:
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