Osteitis fibrosa cystica (pronounced /ˌɒstiːˈaɪtɨs faɪˈbroʊsə ˈsɪstɨkə/, us dict: ŏs′·tē·īt′·əs fī·brō′·sə sĭs′·tə·kə), abbreviated OFC, and also known as osteitis fibrosa or Von Recklinghausen's disease of bone) is a skeletal disorder caused by a surplus of parathyroid hormone from over-active parathyroid glands. This surplus stimulates the activity of osteoclasts, cells that break down bone, in a process known as osteoclastic bone resorption. T...
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