Phenmetrazine is a sympathomimetic drug which acts as a stimulant in the central nervous system. It was previously sold as an anorectic under the trade name Preludin, but has since been removed from the market. It was initially replaced by the weaker analogue phendimetrazine (trade name Bontril), but this is now only rarely prescribed, due to concerns about recreational use.
Other trade names that have been used for Phenmetrazine include: Defenme...
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Phenmetrazine is a sympathomimetic drug which acts as a stimulant in the central nervous system. It was previously sold as an anorectic under the trade name Preludin, but has since been removed from the market. It was initially replaced by the weaker analogue phendimetrazine (trade name Bontril), but this is now only rarely prescribed, due to concerns about recreational use.
Other trade names that have been used for Phenmetrazine include: Defenmetrazin, Fenmetrazin, Oxazimedrine, Phenmetraline.
Phenmetrazine was first patented in Germany in 1952 by Boehringer-Ingelheim, with some pharmacological data published in 1954. It was the result of a search by Thomä and Wick for an anorectic drug without the side-effects of amphetamine. Phenmetrazine was introduced into clinical use in 1954 in Europe.
In clinical use, phenmetrazine produces less nervousness, hyperexcitability, euphoria and insomnia than drugs of the amphetamine family. It tends not to increase heart rate as much as other...
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