Pretibial myxedema

Pretibial myxedema (myxoedema (UK), aka thyroid dermopathy ) is an infiltrative dermopathy, resulting as a rare complication of Graves' disease, with an incidence rate of about 1-5% in patients. It usually presents itself as a waxy, discolored induration of the skin—classically described as having a so-called peau d'orange (orange peel) appearance—on the anterior aspect of the lower legs, spreading to the dorsum of the feet, or as a non-localised... More

Also known as:

  • Pretibial myxoedema,
  • Osler's sign

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