Rous sarcoma virus

Rous sarcoma virus is a retrovirus and is the first oncovirus to have been described: it causes sarcoma in chickens. As with all retroviruses, it reverse transcribes its RNA genome into cDNA before integration into the host DNA. RSV was discovered in 1911 by Peyton Rous, working at Rockefeller University in New York City, by injecting cell free extract of chicken tumour into healthy Plymouth Rock chickens. The extract was found to induce oncogene... more

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  • Rous sarcoma virus

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