A serotonin reuptake inhibitor (SRI) is a type of drug that acts as a reuptake inhibitor for the neurotransmitter serotonin (5-hydroxytryptamine (5-HT)) by blocking the action of the serotonin transporter (SERT). This in turn leads to increased extracellular concentrations of serotonin and, therefore, an increase in serotonergic neurotransmission.
It is important to note that SRIs are not synonymous with selective serotonin reuptake inhibitors (S...
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Drugs with this mechanism of action:
- Sertraline ,
- Fluvoxamine ,
- Olanzapine/fluoxetine ,
- Paroxetine ,
- Desvenlafaxine ,
- Escitalopram ,
- Fluoxetine ,
- Duloxetine ,
- Citalopram ,
- Sibutramine
Drugs:
- Trazodone ,
- Fluvoxamine ,
- Olanzapine/fluoxetine ,
- Sertraline ,
- Paroxetine ,
- Escitalopram ,
- Fluoxetine ,
- Nefazodone ,
- Citalopram ,
- Paroxetine hydrochloride
Also known as:
- Serotonin uptake inhibitor