Sickle-cell disease (SCD), or sickle-cell anaemia (or anemia, SCA) or drepanocytosis, is an autosomal recessive genetic blood disorder with overdominance, characterized by red blood cells that assume an abnormal, rigid, sickle shape. Sickling decreases the cells' flexibility and results in a risk of various complications. The sickling occurs because of a mutation in the hemoglobin gene. Life expectancy is shortened. In 1994, in the US, the averag...
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Also known as:
- sickle-cell anaemia,
- drepanocytosis,
- haemoglobin S,
- SS disease,
- HbSS,
- Sickel cell anemia,
- SCD,
- Sickle cell,
- Sickle cell anemia,
- SCA,
- Sickle cell disease,
- Sickle-cell anemia,
- Sicle cell anemia,
- Sickle-cell disorder
