Sipuleucel-T

A cell-based vaccine composed of autologous antigen-presenting peripheral blood mononuclear cells (enriched for a dendritic cell fraction) that have been exposed to a recombinant protein consisting of granulocyte-macrophage colony-stimulating factor (GM-CSF) fused to prostatic-acid phosphatase (PAP), a protein expressed by prostate cancer cells. Upon administration, the vaccine may stimulate an antitumor T-cell response against tumor cells expres... more

Also known as:

  • Provenge,
  • APC8015

Medicine

Pronunciation:

  • SY-puh-LOO-sel

ATC Code:

  • L01

Pubchem:

  • 47,208,295

CAS Number:

  • 917381-47-6

Drug class:

Brands:

Route of administration:

Active ingredients:

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