Sparfloxacin (spar FLOX a sin), trade names Zagam and Zagam Respipac, is a fluoroquinolone antibiotic used in the treatment of bacterial infections. Zagam is no longer available in the United States.
Sparfloxacin is about 37- 45% bound to proteins in the blood(Shimada et at., 1993; Montay,1996).
Shimada et at. ( 1993) has summarized many of the studies published in Japanese regarding the tissue distribution of sparfloxacin. (high concentrations a...
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Sparfloxacin (spar FLOX a sin), trade names Zagam and Zagam Respipac, is a fluoroquinolone antibiotic used in the treatment of bacterial infections. Zagam is no longer available in the United States.
Sparfloxacin is about 37- 45% bound to proteins in the blood(Shimada et at., 1993; Montay,1996).
Shimada et at. ( 1993) has summarized many of the studies published in Japanese regarding the tissue distribution of sparfloxacin. (high concentrations are achieved in sputum, pleural fluid, skin, lung, prostate, gynecological tissues, breast milk and otolaryngological tissues. *Salivary concentrations are 66-70% of plasma levels, while CSF penetration appears to be somewhat limited with CSF:plasma concentration ratios of only 0.25-0.35.
In rabbits, sparfloxacin achieves very good penetration into the ocular vitreous (54%), cornea (76%) and lens (36%) (Cochereau-Massin et at., 1993).
Brand Name in Bangladesh - SAGA 200 mg, Square pharma
Sparfloxacin, like other Quinolones and fluoroquinolones,...
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