Thalidomide

A synthetic derivative of glutamic acid (alpha-phthalimido-glutarimide) with teratogenic, immunomodulatory, anti-inflammatory and anti-angiogenic properties. Thalidomide acts primarily by inhibiting both the production of tumor necrosis factor alpha (TNF-alpha) in stimulated peripheral monocytes and the activities of interleukins and interferons. This agent also inhibits polymorphonuclear chemotaxis and monocyte phagocytosis. In addition, thalido... More

Formula:

  • C13H10N2O4

Used To Treat:

Legal status:

Also known as:

  • Softenon,
  • Neurosedyn,
  • Contergan,
  • Quietoplex,
  • Sedimide,
  • Nibrol,
  • Talimol,
  • Distaval

Medicine

Pregnancy category:

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Physiologic effect:

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Active moieties:

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Active ingredient of formulation:

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Active moiety of formulation:

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Active moiety of drug:

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Literature Subject

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Chemical Compound

IUPAC ID:

  • (RS)-2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione

Average Molar Mass:

  • 258.23 g/mol
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