Ubiquitin

Ubiquitin is a small, highly-conserved regulatory protein that is ubiquitously expressed in eukaryotes. Ubiquitination (or ubiquitylation) refers to the post-translational modification of a protein by the covalent attachment (via an isopeptide bond) of one or more ubiquitin monomers. The most prominent function of ubiquitin is labeling proteins for proteasomal degradation. Besides this function, ubiquitination also controls the stability, functio... more

Award-Winning Work

Awards Won:

Year Award Award Winner Notes/Description
  • 2004
  • "for the discovery of ubiquitin-mediated protein degradation"
top ↑ top ↑

We can also tell you Ubiquitin is a…

If you know more about Ubiquitin, you can add more facts here »

Similar topics in Freebase

  • Protozoa

    Protozoa

    Protozoa or Cornelius protozoans (from Greek proton proton "first" and ζῷα zoa "animals"; singular protozoon; (the word "protozoan" is originally an adjective, used as a noun) are microorganisms classified as unicellular eukaryotes. While there is no exact definition of the term "protozoan", most...
  • Decision making

    Decision making

    Decision making can be regarded as an outcome of mental processes (cognitive process) leading to the selection of a course of action among several alternatives. Every decision making process produces a final choice. The output can be an action or an opinion of choice. Human performance in decision...
  • Coenzyme A

    Coenzyme A

    Coenzyme A (CoA, CoASH, or HSCoA) is a coenzyme, notable for its role in the synthesis and oxidation of fatty acids, and the oxidation of pyruvate in the citric acid cycle. It is adapted from cysteamine, pantothenate, and adenosine triphosphate. Coenzyme A is synthesized in a five-step process from...
  • Prion

    Prion

    A prion (pronounced /ˈpriː.ɒn/ ( listen)) is an infectious agent that is composed primarily of protein. To date, all such agents that have been discovered propagate by transmitting a mis-folded protein state; the protein itself does not self-replicate and the process is dependent on the presence of...
  • Insulin

    Insulin

    Insulin is a hormone that has extensive effects on metabolism and other body functions, such as vascular compliance. Insulin causes cells in the liver, muscle, and fat tissue to take up glucose from the blood, storing it as glycogen in the liver and muscle, and stopping use of fat as an energy...
  • Spiroptera carcinoma

    Gongylonema neoplasticum is a species of nematode. It was previously known as Spiroptera carcinoma. Under this name, it was the basis of the research that won Johannes Fibiger the 1926 Nobel Prize in Physiology or Medicine. His research indicated that nematode infection led reliably to gastric...
  • Kuru

    Kuru is an incurable degenerative neurological disorder (brain disease) that is a type of transmissible spongiform encephalopathy found in humans. Kuru is believed to be caused by prions and is related to Creutzfeldt-Jakob disease. It is best known for the epidemic that occurred in Papua New Guinea...
  • Femtochemistry

    Femtochemistry is the science that studies chemical reactions on extremely short timescales, approximately 10 seconds (one femtosecond, hence the name). In 1999, Ahmed H. Zewail received the Nobel Prize in Chemistry for his pioneering work in this field. Zewail’s technique uses flashes of laser...
  • Human capital

    Human capital refers to the stock of skills and knowledge embodied in the ability to perform labor so as to produce economic value. It is the skills and knowledge gained by a worker through education and experience. Many early economic theories refer to it simply as workforce, one of three factors...
  • Lupus vulgaris

    Lupus vulgaris are painful cutaneous tuberculosis skin lesions with nodular appearance, most often on the face around nose, eyelids, lips, cheeks and ears. The lesions may ultimately develop into disfiguring skin ulcers if left untreated. In the 19th century, the chronic and progressive nature of...

These people have edited this topic:

Edit this topic
Edit and Show details

Add or delete facts, download data in JSON or RDF formats, and explore topic metadata.

Freebase Logo
What is Freebase?

Freebase is a huge collection of facts, built by people like you. Freebase connects facts in ways other sites can't, giving you new ways to explore millions of subjects.
You can help improve it!

Freebase Attribution

Freebase data is free for use under the CC-BY license.

The original description for Ubiquitin was automatically generated from Wikipedia.org licensed under the GNU Free Documentation License.
[1]
Learn more about Freebase licensing and attribution