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Summary

Rhinovirus (from the Greek rhin- which means "nose") was a genus of the Picornaviridae family of...

Content

Rhinovirus (from the Greek rhin- which means "nose") was a genus of the Picornaviridae family of viruses. It has been now merged into Enteroviruses, a group of Picornaviridae that includes Poliovirus, Coxsackie A virus, and Hepatitis A. Rhinoviri are the most common viral infective agents in humans, and a causative agent of the common cold (about 50% of the cases of the common cold are caused by this virus). It is lytic in nature. There are over a 100 recognized types of rhinoviri that differ based on their varying surface proteins. Rhinoviri are among the smallest viri, with diameters of about only 30 nanometers (other viri such as smallpox and vaccinia viri are 10 times larger at about 300 nanometers). Rhinoviri have single-stranded positive sense RNA genomes of between 7.2 and 8.5 kb in length. At the 5' end of the genome is a virus-encoded protein, and like mammalian mRNA, there is a 3' poly-A tail. Structural proteins are encoded in the 5' region of the genome and non structural at the 3' end. This is the same for all picornaviri. The viral particles themselves are not enveloped and are icosahedral in structure. The rhinovirus also grows best in the temperatures between

Created by: Freebase Data Team Oct 22, 2006
Last edited by: Freebase Data Team Oct 22, 2006

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