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Rhinovirus (from the Greek rhin- which means "nose") was a genus of the Picornaviridae family of...

Rhinovirus (from the Greek rhin- which means "nose") was a genus of the Picornaviridae family of viruses. It has been now merged into Enteroviruses, a group of Picornaviridae that includes Poliovirus and Coxsackie A virus. Rhinovira are the most common viral infective agents in humans, and a causative agent of the common cold. It is lytic in nature. There are 99 recognized types of rhinovira that differ based on their varying surface proteins. Rhinovira are among the smallest vira, with diameters of about only 30 nanometers (other vira such as smallpox and vaccinia vira are 10 times larger at about 300 nanometers). The rhinovirus grows best in the temperatures between 33–35 °C, and this may be why reproduction occurs in the nose. It is sensitive to acidic environments. Rhinovira have single-stranded positive sense RNA genomes of between 7.2 and 8.5 kb in length. At the 5' end of the genome is a virus-encoded protein, and like mammalian mRNA, there is a 3' poly-A tail. Structural proteins are encoded in the 5' region of the genome and non structural at the 3' end. This is the same for all picornavira. The viral particles themselves are not enveloped and are icosahedral in