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Adenoviruses are medium-sized (90–100 nm), nonenveloped (naked) icosahedral viruses composed of a...

Adenoviruses are medium-sized (90–100 nm), nonenveloped (naked) icosahedral viruses composed of a nucleocapsid and a double-stranded linear DNA genome. There are 53 described serotypes in humans, which are responsible for 5–10% of upper respiratory infections in children, and many infections in adults as well. Viruses of the family Adenoviridae infect various species of vertebrates, including humans. Adenoviruses were first isolated in human adenoids, from which the name is derived, and are classified as group I under the Baltimore classification scheme. This family contains the following genera: Classification of Adenoviridae can be complex. In humans, there are 54 accepted human adenovirus types (1-54) in seven species (Human adenovirus A to G): Different types/serotypes are associated with different conditions: When not restricting the subject to human viruses, Adenoviridae can be divided into five genera: Mastadenovirus, Aviadenovirus, Atadenovirus, Siadenovirus and Ichtadenovirus. Adenoviruses represent the largest nonenveloped viruses. Because of their large size, they are able to be transported through the endosome (i.e. envelope fusion is not necessary). The virion also has