A Phase I Evaluation of Azidothymidine (AZT) in Children with Acquired Immune Deficiency Syndrome (AIDS) or AIDS Related Complex (ARC)

Embed this Topic
The study is designed to test the drug zidovudine (AZT) in children, including study of drug levels in various parts of the body fluids, safety of the drug, and its effect on different parts of the body. The effects of any drug, the way a drug enters the bloodstream, the way it is used by the body, and the way the body eliminates the drug may be very different in children compared with adults. The largest group of children who have AIDS are those... more

Medical trial

ClinicalTrials.gov Identifier:

  • NCT00000701

Sponsor:

Type of trial:

Design:

View entire collection »

Phase:

Expected total enrollment:

  • 12

Minimum age for eligibility:

  • 1

Maximum age for eligibility:

  • 12

Eligibility inclusion criteria:

  • * Nutritional support not exceeding 120 calories/kg/day (hyperalimentation or dietary supplements including vitamin, folate, iron supplements).
  • Nutritional support not exceeding 120 calories/kg/day (hyperalimentation or dietary supplements including vitamin, folate, iron supplements).

Eligibility exclusion criteria:

  • Congenital infections such as toxoplasmosis or herpes simplex virus infection in the first month after birth or cytomegalovirus infection in the first 6 months after birth.
  • Hemoglobinopathy including sickle cell anemia.
  • Clinical evidence of active infection of acute nature or active significant or clinically apparent opportunistic infection at time of entry into study.
  • # Asymptomatic with T-lymphocyte deficiency.
  • Asymptomatic viremic patients or those not meeting definition criteria of AIDS related complex (ARC) or AIDS.

Location:

View entire collection »

Health authority:

References:

View entire collection »

Diseases:

Treatment being tested:

top ↑

You can help improve this topic by adding more facts here

Edit this topic
Edit and Show details

Add or delete facts, download data in JSON or RDF formats, and explore topic metadata.

Freebase Logo
What is Freebase?

Freebase is a huge collection of facts, built by people like you. Freebase connects facts in ways other sites can't, giving you new ways to explore millions of subjects.
You can help improve it!

Freebase Attribution

Freebase data is free for use under the CC-BY license.

Learn more about Freebase licensing and attribution